Frequently Asked Questions
What does this test tell us?
A POSITIVE test result for this test indicates that reactive antibodies against SARS-CoV-2 which causes Coronavirus disease (COVID-19) are present, and that you have potentially been exposed to the SARSCoV-2 virus and/or have developed antibodies following vaccination.
A NEGATIVE test result for this test indicates that reactive antibodies against SARS-CoV-2 which causes Coronavirus disease (COVID-19) are not present.
When should my client take the test?
We recommend you do the test at least 3-4 weeks after infection or vaccination, as the rate at which the antibodies develop after exposure to the virus, or a vaccine has been shown to vary. We want to ensure the Covid-19 Antibodies have developed sufficiently reducing the likelihood of a false negative.
If my client tests positive for COVID-19 antibodies does this mean they have developed immunity?
Testing positive indicates a person has developed antibodies to the SARS-CoV-2 virus after being exposed to the virus either through infection or having a vaccine. A positive antibody result DOES NOT require the person to self-isolate (see PCR below) nor does it guarantee immunity. Unfortunately even if the test indicates a person has developed antibodies, the results are to be used for informative purposes only for the moment. Therefore, even with a positive antibody result it is vital to continue to follow the government guidelines on social distancing and COVID-19 general safety. COVID-19 (coronavirus) – HSE.ie This is particularly important given all laboratory tests can also give false positives and false negatives. To help reduce the chance of this anomaly, repeat sampling may therefore be considered.
My client has a negative result but has been vaccinated?
Was the sample taken before our recommended 3-4 weeks wait to ensure that antibody production occurs? Vaccines vary, so an antibody response may only be picked up after the second vaccine. If your client has had their second vaccine and their sample was taken in the recommended time frame of 3-4 weeks you would need to consider a false, negative. To help reduce the chance of this anomaly, repeat sampling may therefore be considered. In addition it is important to take immunosenescence into account. This relates to the gradual deterioration of the immune system with aging which is associated with increased susceptibility to infectious pathogens like SARS-CoV-2 and a poor response to vaccination. Another aspect to consider is that antibodies are not the only way to develop immunity to SARS-CoV2 virus. It is also possible to develop cellular immunity, which may be present even if antibodies are not raised.
My client is taking medication can they do the test?
They should not use this test if they are taking immunosuppressants (e.g., steroids), cancer therapies, antibody therapy, suffer from clotting disease, or are pregnant or breastfeeding.
How is the CNS COVID-19 IgG Antibody test different to a PCR test?
A polymerase chain reaction (PCR) test differs in several ways. One key difference is that this type of test helps to screen people to see if they have an active infection helping to catch those infected early. If positive, this test allows for immediate measures to be taken, such as self-isolation and helps to reduce the spread of the infection. The sample type is different, as in order to detect the virus swabs are taken from the back of the throat and inside the nose. A PCR test measures the SARS-CoV-2 virus’ RNA. It therefore detects the presence of SARS-CoV-2 virus and DOES NOT show if you have developed antibodies to the virus. You would therefore do a PCR test if you have symptoms and suspect you have COVID-19 and wanted to rule it out. If your result is positive using a PCR test, this indicates you have an active infection and should self-isolate as per the government guidelines